A Phase 2 Study of HW211026 in Participants With Actinic Keratosis (NCT07513454) | Clinical Trial Compass
Not Yet RecruitingPhase 2
A Phase 2 Study of HW211026 in Participants With Actinic Keratosis
80 participantsStarted 2026-05
Plain-language summary
This is a multicenter, randomized, open-label, parallel-group, Phase II clinical trial designed to evaluate the efficacy and safety of HW211026 in adult patients with actinic keratosis.
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Key Inclusion Criteria:
* Aged ≥ 18 years, male or female.
* At least 2 clinically typical target actinic keratosis lesions on the face.
* Willing to avoid direct sun or ultraviolet exposure to the treatment area during the trial.
* Fully informed about the study, voluntarily sign the informed consent form, and be able to comply with study procedures and follow-up examination requirements.
Key Exclusion Criteria:
* Clinically atypical and/or rapidly changing actinic keratosis lesions, such as hypertrophic lesions, hyperkeratotic lesions, and/or cutaneous horns.
* Presence of incompletely healed wounds or suspected squamous cell carcinoma, basal cell carcinoma, or other malignant tumors within 5 cm of the actinic keratosis lesions.
* Participants with other skin diseases or skin conditions that, in the investigator's judgment, may interfere with the evaluation of safety or efficacy.
* Participants who are unable to discontinue immunomodulators, immunosuppressants, cytotoxic agents, or corticosteroids from 1 month prior to signing the informed consent form until study completion or early withdrawal.
* Participants who have undergone major surgery within 3 months prior to screening, or who plan to undergo surgery during the trial, as determined by the investigator.
* Participants who have participated in any investigational drug clinical trial and received an investigational product within 3 months prior to screening.
What they're measuring
1
Complete Clearance Rate
Timeframe: Day 56
Trial details
NCT IDNCT07513454
SponsorHubei Bio-Pharmaceutical Industrial Technological Institute Inc.