Effectiveness of Unilateral Transversus Abdominis Plane (TAP) Block vs Bilateral TAP Block in Pat… (NCT07513012) | Clinical Trial Compass
By InvitationNot Applicable
Effectiveness of Unilateral Transversus Abdominis Plane (TAP) Block vs Bilateral TAP Block in Patients Undergoing Laparoscopic Cholecystectomy.
Pakistan82 participantsStarted 2025-11-04
Plain-language summary
In this study, patients undergoing laparoscopic cholecystectomy will be randomly divided into 2 groups after consent. Group A patients will be administered a one-sided (right unilateral) regional TAP block and group B patients will be administered the same block on both sides (bilateral) and the effects in terms of post surgery pain during the 1st 24 hours, nausea vomiting, and the need and dosage of intravenous analgesic and antiemetic will be studied to see whether one technique is superior to the other or not.
Who can participate
Age range18 Years – 80 Years
SexALL
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Inclusion criteria
✓. Both genders between 18-80 years with symptomatic gallstone disease.
✓. Diagnosed patients that are fit for laparoscopic cholecystectomy, having ASA status of I, II or III).
✓. No documented allergies or adverse reactions to local anesthetics used.
✓. Patients consenting to participate in the study.
Exclusion criteria
✕. Non consenting individuals.
✕. Active skin infection at TAP block site i.e. triangle of petit.
✕. Patients with coagulopathies.
✕. Patients with chronic pain disorders and chronic use of analgesics.
✕. Patients with chronic liver and kidney diseases.
✕. Patients with alcohol, opioid or other substance addiction.
✕
What they're measuring
1
Mean time to first request for rescue analgesia
Timeframe: Time from completion of surgery to first request for rescue analgesia till completion of 24 hrs
2
The amount of postoperative IV opioids required as rescue analgesia in first 24 hrs
Timeframe: From end of surgery up to 24 hours postoperatively.