Assessment of Two Soft Tissue Augmentation Using Acellular Dermis Around Dental Implants (NCT07512245) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Assessment of Two Soft Tissue Augmentation Using Acellular Dermis Around Dental Implants
United States40 participantsStarted 2026-06
Plain-language summary
This study aims to compare soft tissue grafting with acellular dermis at Phase I or Phase II dental implant surgery.
Who can participate
Age range18 Years – 85 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* English speaking
* At least 18 years old
* Must be a patient of the UAB Dental School
* Able to read and understand informed consent document
* Patients presenting with a single edentulous site planned for dental implant placement deemed deficient in soft tissue peri-implant phenotype (\> 2mm width of keratinized tissue, \< 1mm marginal soft tissue thickness, and/or \> 2mm vertical soft tissue height)
* Presence of periodontally healthy, non-carious neighboring teeth and/or healthy restored dental implants on either side of edentulous site planned for dental implant placement.
* No anticipated need for surgical and/or endodontic care at teeth adjacent to the proposed surgical site during the study period.
Exclusion Criteria:
* Non-English speaking
* Less than 18 years old
* Smokers/tobacco users (\>10 cigarettes/day)
* Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing
* Edentulous sites treatment planned for dental implant placement with adequate implant site soft tissue quality/quantity (\> 2mm width of keratinized tissue, \> 1mm marginal soft tissue thickness, and/or \> 2mm vertical soft tissue height).
* Absence of adjacent teeth/implants on either side of the tooth to be extracted and/or edentulous sites where 2 or more adjacent implants are planned.
What they're measuring
1
Width of buccal keratinized tissue at dental implant sites
Timeframe: From baseline to 6 months
2
Thickness of buccal keratinized tissue 2mm from the gingival margin of the dental implant sites
Timeframe: From baseline to 6 months
3
Vertical height of peri-implant soft tissues
Timeframe: From Baseline to 6 months
4
Radiographic marginal bone loss
Timeframe: From baseline to 6 months
5
Patient centered outcomes using the Visual Analog Scale (VAS)