Not Yet RecruitingNot Applicable

High Resolution Pharyngeal Manometry (HRPM) Biofeedback

United States50 participantsStarted 2026-05-01

Plain-language summary

The purpose of this study is to quantify the added benefit of visual biofeedback from High Resolution Pharyngeal Manometry (HRPM) for swallowing rehabilitation. Primary aims including assessing changes in swallowing biomechanics (pressure generation, timing) during swallow maneuvers with and without HRPM visual biofeedback. Secondary aim includes participant attitudes related to visual biofeedback and the experience of HRPM.

Who can participate

Age range18 Years – 40 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Participants must be independent community dwelling adults.
✓. Participants must be between the ages of 18-40 years old.
✓. Willingness to consent and participate in the study procedures.
✓. No reported dysphagia or difficulty swallowing evidenced by an EAT-10 Score \<3.

Exclusion criteria

✕. Known structural or neurological causes of dysphagia (e.g., stroke, brain injury, or head/neck cancer).
✕. Recent or remote history of swallowing therapy; familiarity with swallowing maneuvers from relevant coursework as applicable (i.e., speech language pathology students).

What they're measuring

Change in pharyngeal contractile integral (PhCI) (mmHg) with and without visual biofeedback via HRPM

Timeframe: Baseline (without HRPM), with HRPM (up to 2 minutes)

Change in pharyngoesophageal Segment (PES) opening duration (ms) with and without visual biofeedback via HRPM

Timeframe: Baseline (without HRPM), with HRPM (up to 2 minutes)

Change in PES pressure with visual biofeedback via HRPM with and without visual biofeedback via HRPM

Timeframe: Baseline (without HRPM), with HRPM (up to 2 minutes)

Trial details

NCT IDNCT07508059

SponsorNYU Langone Health

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-02-01

Contact for this trial

Sonja Molfenter

212-992-7694 Smm16@nyu.edu

View on ClinicalTrials.gov More Healthy trials

Plain-language summary

Who can participate

Age range18 Years – 40 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Participants must be independent community dwelling adults.
✓. Participants must be between the ages of 18-40 years old.
✓. Willingness to consent and participate in the study procedures.
✓. No reported dysphagia or difficulty swallowing evidenced by an EAT-10 Score \<3.

Exclusion criteria

✕. Known structural or neurological causes of dysphagia (e.g., stroke, brain injury, or head/neck cancer).
✕. Recent or remote history of swallowing therapy; familiarity with swallowing maneuvers from relevant coursework as applicable (i.e., speech language pathology students).

What they're measuring

Change in pharyngeal contractile integral (PhCI) (mmHg) with and without visual biofeedback via HRPM

Timeframe: Baseline (without HRPM), with HRPM (up to 2 minutes)

Change in pharyngoesophageal Segment (PES) opening duration (ms) with and without visual biofeedback via HRPM

Timeframe: Baseline (without HRPM), with HRPM (up to 2 minutes)

Change in PES pressure with visual biofeedback via HRPM with and without visual biofeedback via HRPM

Timeframe: Baseline (without HRPM), with HRPM (up to 2 minutes)