Atorvastatin Therapy in the Treatment of Dyslipidemia in Children With Steroid Sensitive Nephroti… (NCT07497776) | Clinical Trial Compass
CompletedPhase 4
Atorvastatin Therapy in the Treatment of Dyslipidemia in Children With Steroid Sensitive Nephrotic Syndrome
Bangladesh100 participantsStarted 2024-01-27
Plain-language summary
To evaluate the effectiveness and safety of Atorvastatin therapy in children with dyslipidemia in steroid sensitive nephrotic syndrome.
Who can participate
Age range8 Years – 18 Years
SexALL
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Inclusion Criteria:
* Children aged 8-18 years with known cases of steroid sensitive nephrotic syndrome
* LDL ≥ 130 mg/dl in two consecutive serum fasting lipid profile, at least 4 weeks apart
* while on remission
* free of acute infection.
Exclusion criteria
* Children with previously diagnosed hyperlipidemia other than Nephrotic Syndrome.
* Children with steroid resistant nephrotic syndrome
* Children already on lipid lowering drugs
* Secondary nephrotic syndrome.
* Those parents/patients who refused to participate.
4\. Secondary nephrotic syndrome (SLE, amyloidosis etc.) 5. Nephrotic syndrome (initial episode). 6. Children taking Anti TB drug or anticonvulsant drugs. 7. Children having any active liver disease.
What they're measuring
1
percentage of patients achieving target levels of lipid profile
Timeframe: 6 months
Trial details
NCT IDNCT07497776
SponsorNational Institute of Kidney Disease and Urology (NIKDU)