This study will evaluate safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending doses (SAD) (Part 1a), multiple ascending doses (MAD) (Part 1b), and the food effect (Part 1c) of RO7763505 in healthy adult participant. In Part 2, the safety, tolerability, PK and PD of multiple doses of RO7763505 in participants with stable coronary artery diseases (CAD).
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Part 1a and Part 1b: Percentage of Participants With Adverse Events (AEs)
Timeframe: Part 1a: Approximately up to 2 Weeks; Part 1b: Approximately up to 3 Weeks
Part 1c: Plasma Concentration of RO7763505 in Fasted and fed State
Timeframe: Approximately up to 3 Weeks
Part 2: Percentage of Participants With AEs
Timeframe: Approximately up to 6 Weeks
Reference Study ID Number: BP46355 https://forpatients.roche.com/