Motorized Prostheses for Lower-limb Amputees (NCT07486063) | Clinical Trial Compass
RecruitingEarly Phase 1
Motorized Prostheses for Lower-limb Amputees
United States40 participantsStarted 2025-07-01
Plain-language summary
The investigators will assess biomechanical and functional mobility outcomes in individuals with unilateral, above-knee amputations using different knee/ankle configurations of a lightweight powered prosthesis and different volitional controllers in individuals with unilateral, above-knee amputations.
Who can participate
Age range18 Years – 80 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Our inclusion criteria will be
* Above-knee amputation
* K2/K3/K4 ambulators
* At least 18 years old
* At least one year since amputation
* At least six months since the definitive prosthesis fitting
* Currently prescribed and using a mechanically passive or microprocessor-controlled prosthesis
Our exclusion criteria will be
* Over 350 lbs. body weight, the weight limit for our safety suspension systems
* Cognitive deficits or visual impairment that could impair their ability to give informed consent or to follow simple instructions during the experiments
* Pregnant women due to elevated safety concerns for this population
* Co-morbidity that limits their ability to participate in the study protocol (e.g., stroke, pacemaker placement that would interfere with the powered prosthesis, severe ischemia, cardiac disease, etc.)
* Adults who are unable to consent
* Individuals who are not yet adults (infants, children, teenagers)
* Individuals who use a wheelchair for mobility both outdoors and indoors because they may not be able to perform the necessary activities with their passive prosthesis or the powered prosthesis
* Prisoners, due to concerns with informed consent
What they're measuring
1
Amputee Mobility Predictor with Prosthesis (AMPPRO)