Efficacy of Proximal Median Nerve Release (NCT07484100) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Efficacy of Proximal Median Nerve Release
Finland160 participantsStarted 2026-03-01
Plain-language summary
A multi-center randomized controlled clinical trial which determines the efficacy of proximal median nerve release in patients with persistent proximal median nerve compression. The primary outcome is patient reported improvement of symptoms on a 7-point Likert scale at 6 months after the randomization to treatment group.
Who can participate
Age range18 Years
SexALL
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Inclusion criteria
✓. Clinically diagnosed PMNC
✓. If the patient has clinically and electrodiagnostically confirmed carpal tunnel syndrome, at least 6 months must have passed since surgical treatment
✓. Age 18 or over
✓. Ability to understand Finnish
✓. Ability to complete electronic questionnaires independently
✓. Willingness to participate in research and follow research instructions
✓. Provision of informed consent from the participant
Exclusion criteria
✕. Nerve root disorder findings in ENMG
✕. Thoracic outlet syndrome, TOS
✕. Other neurological condition that causes upper limb symptoms such as MS, previous nerve injury
✕. Active rheumatoid arthritis or any other active inflammatory joint disease that affects hand function
✕. Significant compression symptoms of another peripheral nerve in association with PMNC
✕. Other upper extremity operation performed less than 6 months ago
✕. Another disease or condition that accounts for most of the patient's symptoms