A Study Of T1/Tref Intubating Conditions (NCT07483164) | Clinical Trial Compass
By InvitationNot Applicable
A Study Of T1/Tref Intubating Conditions
United States108 participantsStarted 2026-03-23
Plain-language summary
The purpose of this study is to determine the maximum ratio of the twitch amplitude (T1) to the reference twitch (Tref) amplitude (T1/Tref) that provides excellent intubating conditions.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Age \> or = 18 years old
* Patients willing to participate and provide an integrated, informed consent
Exclusion Criteria
* Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury.
* Patients with systemic neuromuscular diseases such as myasthenia gravis.
* Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents, i.e., severe renal impairment requiring dialysis or end-stage liver disease.
* Patients requiring a rapid sequence induction for airway protection.
* Patients deemed ineligible for surgery, including pregnancy (as determined by standard of care testing).
What they're measuring
1
Maximum T1/Tref ratio associated with excellent intubating conditions