Safety and Efficacy of LVD + C-TACE + Tis/Len for Unresectable Right-Liver HCC

Inclusion Criteria: * Age 18-75 years. * Confirmed HCC (histologically or by AASLD clinical criteria). * Initially unresectable HCC limited to the right liver (due to insufficient FLR or tumor characteristics). * Child-Pugh score ≤ 7 (Class A or early B). * ECOG Performance Status of 0 or 1. * Adequate organ function (marrow, hepatic, and renal). Exclusion Criteria: * Extrahepatic metastasis. * Portal vein tumor thrombus involving the main trunk (Vp4). * Previous systemic therapy for HCC. * Active autoimmune disease or history of organ transplantation. * Contraindications to LVD, TACE, or the study drugs