RecruitingNot Applicable

Feasibility of Remotely Measured Activity Behavior for Individuals With Functional Neurologic Disorder

Canada40 participantsStarted 2026-04-16

Plain-language summary

This study evaluates whether remotely measured daily activity behavior, captured through a thigh-worn accelerometer, can serve as a reliable and ecologically valid indicator of symptom impact in individuals with Functional Neurologic Disorder (FND). Current clinician-rated assessments capture only a single time point and do not reflect day-to-day symptom variability or functional impact. The study will (1) assess the feasibility of continuous activity monitoring in people with FND, (2) examine associations between activity behavior and established clinician- and patient-reported FND measures, and (3) qualitatively explore participants' lived experiences of daily activity. Findings aim to address a critical gap in understanding real-world function in this heterogeneous population.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Participants with FND: •Neurologist-confirmed diagnosis of functional neurologic disorder with motor symptoms, sensory symptoms, dizziness, and/or seizures Healthy Controls: * Roughly matched to participants with FND for age and sex * Free from major disease that affects mobility (e.g., neurologic, movement, cardiac, pulmonary, renal, and psychiatric disorders) by history. Exclusion Criteria: Participants with FND * Physical or cognitive symptoms impairing ability to engage with the protocol (e.g., seizure frequency \> 10/day). * Diagnosis of other major neurologic, cardiovascular, musculoskeletal, or psychiatric disorder that affects mobility as determined by the principal investigator

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Feasibility of remotely assessed activity behavior with thigh-mounted accelerometry: enrollment

Timeframe: 10 Months

Adherence to thigh-mounted accelerometer use

Timeframe: From baseline through study completion, an average of 1 week.

Feasibility of remotely assessed activity behavior with thigh-mounted accelerometry: retainment

Timeframe: From baseline through study completion, an average of 1 week.

Acceptability of remotely assessed activity behavior with thigh-mounted accelerometry

Timeframe: Visit 2

Trial details

NCT IDNCT07478666

SponsorUniversity of Colorado, Denver

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-04-30

Contact for this trial

Elliot J Gann, DPT

650-282-0897 elliot.gann@cuanschutz.edu

View on ClinicalTrials.gov More Functional Neurological Disorder trials

Plain-language summary

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Feasibility of remotely assessed activity behavior with thigh-mounted accelerometry: enrollment

Timeframe: 10 Months

Adherence to thigh-mounted accelerometer use

Timeframe: From baseline through study completion, an average of 1 week.

Feasibility of remotely assessed activity behavior with thigh-mounted accelerometry: retainment

Timeframe: From baseline through study completion, an average of 1 week.

Acceptability of remotely assessed activity behavior with thigh-mounted accelerometry

Timeframe: Visit 2