This is a Phase I/II clinical study conducted in participants with relapsed/refractory aggressive B-cell lymphoma. The study aims to evaluate the safety, tolerability, pharmacokinetic characteristics and preliminary efficacy of SYS6055 Injection in participants with relapsed/refractory aggressive B-cell lymphoma, and to provide a basis for the recommended dosing regimen in subsequent studies.
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Dose-limiting toxicities (DLTs)
Timeframe: Dose-limiting toxicities (DLTs) will be assessed 28 days after the first dose.
Occurrence of Adverse Events (AE) and Serious Adverse Events (SAE)
Timeframe: Up to 24 months after administration of 6055
Recommended Phase 2 Dose (RP2D) or Maximum Tolerated Dose (MTD) of SYS6055
Timeframe: through study completion, an average of 3 years