This study aims to directly compare and contrast swallowing pressure and impedance measurements obtained from two high-resolution manometry (HRM) systems: the Laborie LMT Pharyngeal System and the Medtronic ManoScan ESO HRM System in healthy adult volunteers. The primary objective is to determine how differences in catheter diameter, sensor configuration, and acquisition platforms influence measurement outcomes. Twenty-five healthy adults will participate in a single, approximately 2-hour visit; the study will be open for one year for data collection and two years for data analysis.
Age range
18 Years – 99 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Base of tongue pressure
Timeframe: data collected during 1 study visit (up to 2 hours)
Hypopharyngeal peak pressure
Timeframe: data collected during 1 study visit (up to 2 hours)
Pharyngeal Contractile Integral (PhCI)
Timeframe: data collected during 1 study visit (up to 2 hours)
Pressure rise time
Timeframe: data collected during 1 study visit (up to 2 hours)
Contractile front velocity
Timeframe: data collected during 1 study visit (up to 2 hours)
Upper Esophageal Sphincter (UES) resting pressure
Timeframe: data collected during 1 study visit (up to 2 hours)
UES peak contraction pressure
Timeframe: data collected during 1 study visit (up to 2 hours)
UES relaxation nadir pressure
Timeframe: data collected during 1 study visit (up to 2 hours)
UES relaxation duration
Timeframe: data collected during 1 study visit (up to 2 hours)
Nadir impedance
Timeframe: data collected during 1 study visit (up to 2 hours)
Bolus presence time
Timeframe: data collected during 1 study visit (up to 2 hours)
Flow interval
Timeframe: data collected during 1 study visit (up to 2 hours)
Pressure-flow index component
Timeframe: data collected during 1 study visit (up to 2 hours)
Timing relationships (onset-to-peak intervals)
Timeframe: data collected during 1 study visit (up to 2 hours)
Construction of Spatial pressure distribution maps
Timeframe: data collected during 1 study visit (up to 2 hours)