Mandibular Biological Drilling at Different Speeds for Dental Implant Placement (NCT07474454) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Mandibular Biological Drilling at Different Speeds for Dental Implant Placement
39 participantsStarted 2026-03-15
Plain-language summary
This randomized controlled clinical trial aims to evaluate the effect of different biological drilling speeds (50, 150, and 300 rpm) during implant osteotomy preparation in the mandible on marginal bone level changes and implant stability. Thirty-nine patients requiring a single dental implant in the mandible will be randomly allocated into three groups according to drilling speed. All implants will be placed using a biological drilling protocol without irrigation. Implant stability will be measured using resonance frequency analysis at implant placement and follow-up visits. Marginal bone levels will be evaluated radiographically using standardized periapical radiographs during the follow-up period up to 12 months. The study aims to determine whether different low-speed drilling protocols influence peri-implant bone remodeling and implant stability.
Who can participate
Age range
20 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adult patients aged 20-60 years.
* Partially edentulous patients requiring a single dental implant in the mandible.
* Adequate bone height and width at the implant site to accommodate the planned implant dimensions without the need for advanced grafting.
* Good oral hygiene (full-mouth plaque and bleeding scores within acceptable limits).
* Patients willing to participate, available for 12-month follow-up, and able to sign informed consent.
Exclusion Criteria:
* Systemic diseases or conditions that may compromise bone healing (e.g. uncontrolled diabetes, immunosuppression, recent radiotherapy in head and neck region).
* Smoking more than 10 cigarettes/day or heavy vaping.
* Pregnant or lactating women.
* History of bisphosphonate or other anti-resorptive therapy affecting bone metabolism.
* Active periodontal disease or poor oral hygiene.
* Acute infection or pathology at the planned implant site.
* Need for simultaneous major bone grafting at the same site.
* Bruxism or severe parafunctional habits.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Marginal Bone Level Change
Timeframe: Baseline (Surgery) and 12 months postoperatively.