Embolization of Ovarian Vein and Pelvic Venous Reservoir for Treatment of Secondary Pelvic Conges… (NCT07472504) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Embolization of Ovarian Vein and Pelvic Venous Reservoir for Treatment of Secondary Pelvic Congestion Syndrome
100 participantsStarted 2026-03-01
Plain-language summary
Transcatheter Embolization of Ovarian Vein and Pelvic Venous Reservoir for Treatment of Pelvic Congestion Syndrome Secondary to May-Thurner Syndrome.
This study aims to prospectively evaluate the short-term clinical outcomes and the incidence of post-embolization stenting for residual symptoms.
Who can participate
Age range18 Years – 50 Years
SexFEMALE
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Inclusion Criteria:
* • Adult females aged 18 -60 years.
* Clinical symptoms consistent with PCS \>6 months refractory to conservative treatment(e.g., chronic pelvic pain (CPP) of at least 6 months duration, unresponsive to conventional pain management strategies and worsening with standing, dyspareunia, pelvic heaviness, presence of vulvar/perineal/thigh varices and ovarian point tenderness during examination in patients with history of post-coital pain).
* Symptom Correlation: Pelvic pain is deemed to be significantly attributable to the identified iliac venous compression after multidisciplinary assessment for exclusion of the other causes of chronic pelvic pain (e.g., gynaecologist, urologist, pain specialist).
* Imaging-confirmed non-thrombotic iliac venous outflow stenosis or occlusion with ovarian and/or pelvic venous reservoir reflux (e.g., cross-sectional area reduction on direct CT venography, MR venography or digital subtraction angiography)
* Informed Consent: Willingness and ability to provide written informed consent prior to study-specific procedures.
* Adherence to Follow-up: Willingness and ability to comply with scheduled follow-up visits and study procedures.
Exclusion Criteria:
* Primary Pelvic Congestion Syndrome (PCS) only: Patients with significant pelvic venous reflux (e.g., ovarian or internal iliac vein reflux) without demonstrable and significant iliac venous outflow obstruction (i.e., primary PCS without secondary component).
* Pelvic…
What they're measuring
1
Change in pelvic pain severity using VAS pain score as scale
Timeframe: 12 months
2
The primary outcome measure is designed to assess the significant reduction in pelvic pain severity