CompletedNot Applicable

Povidone-Iodine Nasal Irrigation After Surgery for Chronic Rhinosinusitis

South Korea48 participantsStarted 2021-10-13

Plain-language summary

This prospective randomized controlled trial evaluates the effectiveness and safety of different nasal irrigation solutions for postoperative care after endoscopic sinus surgery in patients with chronic rhinosinusitis. Patients undergoing endoscopic sinus surgery will be randomly assigned to receive nasal irrigation with normal saline, mucomyst, or diluted povidone-iodine solution for three months after surgery. Clinical outcomes, symptom scores, endoscopic findings, and potential ototoxic effects will be evaluated to compare the effectiveness and safety of these irrigation methods.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients diagnosed with chronic rhinosinusitis * Patients who underwent endoscopic sinus surgery (ESS) * Patients who performed postoperative nasal irrigation for 3 months * Patients who completed the follow-up evaluation and agreed to participate in the study Exclusion Criteria: * History of chronic otitis media * Presence of otitis media with effusion at the time of evaluation * History of previous middle ear surgery * Known allergy to povidone-iodine * Incomplete follow-up data * Refusal to participate in the study

What they're measuring

Lund-Kennedy Endoscopic Score

Timeframe: 3 months after endoscopic sinus surgery

Hearing function assessed by pure tone audiometry (PTA)

Timeframe: 3 months after endoscopic sinus surgery

Trial details

NCT IDNCT07470242

SponsorPusan National University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-03-07

View on ClinicalTrials.gov More Chronic Rhinosinusitis trials