CompletedNot Applicable

Post-exercise Rehydration: A Randomised Cross-over Trial Comparing a 100% Fruit Beverage, a Glucose-based Sports Drink, and Water

United Kingdom17 participantsStarted 2024-11-08

Plain-language summary

It is well-established that exercise has many health benefits. During exercise in temperate/hot conditions, sweating is necessary to dissipate heat. This sweating typically results in dehydration, which may impair physical and mental performance. Therefore, following exercise, effective rehydration is important to restore an optimal hydration state and therefore physical and mental performance. If an individual only rehydrates with water, though, it is unlikely that they will fully rehydrate as plain water is not very well-retained by the body, due to its lack of carbohydrate and electrolytes. For this reason, sports/ hydration drinks are likely to aid in better rehydration, due to their carbohydrate and electrolyte content. This project aims to compare the rehydration effectiveness and glucose responses to two sports / hydration drinks and water (with different carbohydrate and electrolyte contents).

Who can participate

Age range

18 Years – 50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: \- Training/performing \> 1 hrs a week Exclusion Criteria: * Smoker. * Pregnant, attempting to become pregnant, or breastfeeding. * Diabetic. * You have adverse events/reactions in response to fingertip capillary blood sampling which includes, but is not limited to; fainting and/or serious bruising. * History of heat-related illness. * History of heart failure, pulmonary hypertension, embolism, or other pulmonary heart disease. * Previously diagnosed with COPD, emphysema, bronchitis or similar respiratory illness. * Have a history of severe allergic reactions. * History of kidney issues. * Regular use of non-steroidal anti-inflammatory medications. * Any other medical conditions / medications that may interfere with an individuals ability to safely perform exercise in the heat and experience dehydration. * Allergies/intolerances to any of the following ingredients: Glucose Syrup, Acid (Citric Acid), Acidity Regulator (Sodium Citrate), Extract of Black Carrot, Watermelon, pomegranate, lime, Preservatives (Potassium Sorbate, Dimethyl Dicarbonate), Stabilisers (Acacia Gum), Sweeteners (Aspartame, Acesulfame K), Antioxidant (Ascorbic Acid), Flavourings, Niacin (Vitamin B3). * Elite athlete subject to doping tests

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Net water Balance

Timeframe: Baseline (pre-exercise), post-exercise, and 0, 1, 2, 3, and 4 h post-rehydration

Cumulative urine volume

Timeframe: 0, 1, 2, 3, and 4 h post-rehydration

Total urine volume

Timeframe: Sum of urine produced at 0, 1, 2, 3, and 4 h post-rehydration

Water retention

Timeframe: 4 h post-rehydration

Trial details

NCT IDNCT07468539

SponsorNottingham Trent University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05-22

View on ClinicalTrials.gov More Dehydration trials