RecruitingPhase 3

Development and Application of a Nurse-Led Preemptive Symptom Management Protocol for Head and Neck Cancer Patients Undergoing Radiation Therapy

China170 participantsStarted 2026-03-15

Plain-language summary

The aim of this study is to investigate whether a nurse-led preemptive symptom management protocol can reduce the radiation therapy interruption rate in patients with head and neck cancer compared to conventional care models.

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion criteria

✓. Patients had pathologically confirmed malignant head and neck tumors without distant metastasis.
✓. Patient age ≥18 years; Patients were scheduled to undergo either postoperative adjuvant radiotherapy or radical radiotherapy, with or without concurrent chemotherapy.
✓. Baseline ECOG (Eastern Cooperative Oncology Group) score 0-2;
✓. Good cognitive and reading skills, able to complete the questionnaire survey.

Exclusion criteria

✕. Presence of other malignant tumors aside from head and neck malignancies;
✕. A history of prior head and neck radiotherapy;
✕. Mental illness or cognitive impairments;
✕. Uncontrolled systemic diseases that could significantly affect their QoL.

What they're measuring

Radiotherapy interruption rate

Timeframe: The time period is the period from the start of radiotherapy to the completion of radiotherapy.The evaluation period is approximately 6 weeks and 6.5 weeks.

Trial details

NCT IDNCT07467083

SponsorWest China Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-03-01

View on ClinicalTrials.gov More Head and Neck Cancer trials