A Single-Dose, Randomized, Open-Label, 2-Way Crossover Study to Evaluate the Dose-Proportionality, Safety, and Tolerability of TNX-102 SL (Cyclobenzaprine HCl Sublingual Tablets) in Healthy Japanese and Chinese Subjects

Inclusion criteria

• . Is of childbearing potential who are sexually active with a male partner must be willing to use one of the following acceptable contraceptive methods throughout the study and for 30 days after the last study drug administration:
• . Is of non-childbearing potential, defined as surgically sterile (ie, has undergone complete hysterectomy, bilateral oophorectomy, or tubal ligation), or is in a postmenopausal state (ie, at least 1 year without menses and without an alternative medical condition prior to the Screening visit) 5. Aged at least 18 years but not older than 65 years 6. Body mass index (BMI) within 17.5 kg/m2 to 32.0 kg/m2 and a minimum body weight of 50.0 kg for males and 45.0 kg for females 7. Non- or ex-smoker (An ex-smoker is defined as someone who completely stopped using oral or other tobacco products (including betel nut) for at least 90 days prior to Screening) 8. Have no clinically significant diseases captured in the medical history or evidence of clinically significant findings on the physical examination (including vital signs) and/or ECG, as determined by an investigator