The goal of this observational study is to learn whether routine stool tests can detect changes in gut function 6 months after two common types of weight loss surgery: sleeve gastrectomy and gastric bypass (including mini gastric bypass and Roux-en-Y gastric bypass). The main questions it aims to answer are: Do stool tests show more signs of undigested food or carbohydrate malabsorption after gastric bypass compared to sleeve gastrectomy? Do signs of gut inflammation in stool (like fecal calprotectin) decrease after surgery, and does this relate to improvements in blood sugar and weight loss? Can simple stool test results at 6 months predict how much weight a person loses or how well their diabetes improves? Researchers will compare stool test results between the two surgery groups (sleeve gastrectomy vs. gastric bypass) to see if the type of surgery leads to different changes in gut health. Participants will: Provide a stool sample before surgery and again 6 months after surgery Provide a blood sample at the same time points to measure weight, blood sugar, and cholesterol Undergo their planned weight loss surgery as part of their regular medical care
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Change in Stool pH
Timeframe: At Baseline and at 6 months postoperatively
Change in Fecal Calprotectin Level
Timeframe: At Baseline and at 6 months postoperatively
Presence of Undigested Food Particles
Timeframe: At Baseline and at 6 months postoperatively
Presence of Reducing Substances
Timeframe: At Baseline and at 6 months postoperatively
Change in Stool White Blood Cell Count
Timeframe: At Baseline and at 6 months postoperatively
Change in Stool Red Blood Cell Count
Timeframe: At Baseline and at 6 months postoperatively