Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy (NCT07460310) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy
200 participantsStarted 2026-03-01
Plain-language summary
Ankle arthroscopy is increasingly performed as a day-case procedure, making rapid recovery and efficient discharge critical. Anesthetic technique substantially influences postoperative recovery, yet high-quality evidence comparing anesthetic strategies in ankle arthroscopy is limited.
This multicenter randomized trial compares total intravenous anesthesia with propofol plus peripheral nerve block (PNB), general anesthesia plus PNB, and spinal anesthesia, with PACU-I recovery time as the primary outcome. Secondary outcomes include postoperative pain, opioid consumption, hospital length of stay, adverse events, recovery quality, satisfaction, limb weakness, and intraoperative hemodynamics.
Who can participate
Age range18 Years ā 65 Years
SexALL
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Inclusion Criteria:
* Full understanding of the study procedures and methods, with a signed written informed consent form.
* Aged 18 to 65 years, of either sex.
* Scheduled for elective unilateral minimally invasive ankle surgery.
* American Society of Anesthesiologists (ASA) physical status classification I or II.
* Body Mass Index (BMI) between 16 and 32 kg/m\^2
Exclusion Criteria:
* Known hypersensitivity or allergy to any study medications or existing contraindications to anesthesia.
* Chronic obstructive pulmonary disease (COPD) or unstable asthma.
* History of difficult airway management, poorly controlled gastroesophageal reflux disease (GERD), or a known risk of aspiration.
* Anticipated surgical duration exceeding 3 hours.
* History of chronic preoperative opioid use or dependence.
* History of severe postoperative adverse reactions (e.g., severe postoperative nausea and vomiting).
* Pregnancy or lactation.
* History of seizure disorders or epilepsy.
* Severe peripheral neuropathy.
* Any other condition that, in the opinion of the investigator, would preclude safe participation in the study.
What they're measuring
1
Duration of stay in Phase I PACU
Timeframe: On the day of surgery
Trial details
NCT IDNCT07460310
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University