Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy (NCT07460310) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy
200 participantsStarted 2026-03-01
Plain-language summary
Ankle arthroscopy is increasingly performed as a day-case procedure, making rapid recovery and efficient discharge critical. Anesthetic technique substantially influences postoperative recovery, yet high-quality evidence comparing anesthetic strategies in ankle arthroscopy is limited.
This multicenter randomized trial compares total intravenous anesthesia with propofol plus peripheral nerve block (PNB), general anesthesia plus PNB, and spinal anesthesia, with PACU-I recovery time as the primary outcome. Secondary outcomes include postoperative pain, opioid consumption, hospital length of stay, adverse events, recovery quality, satisfaction, limb weakness, and intraoperative hemodynamics.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Full understanding of the study procedures and methods, with a signed written informed consent form.
* Aged 18 to 65 years, of either sex.
* Scheduled for elective unilateral minimally invasive ankle surgery.
* American Society of Anesthesiologists (ASA) physical status classification I or II.
* Body Mass Index (BMI) between 16 and 32 kg/m\^2
Exclusion Criteria:
* Known hypersensitivity or allergy to any study medications or existing contraindications to anesthesia.
* Chronic obstructive pulmonary disease (COPD) or unstable asthma.
* History of difficult airway management, poorly controlled gastroesophageal reflux disease (GERD), or a known risk of aspiration.
* Anticipated surgical duration exceeding 3 hours.
* History of chronic preoperative opioid use or dependence.
* History of severe postoperative adverse reactions (e.g., severe postoperative nausea and vomiting).
* Pregnancy or lactation.
* History of seizure disorders or epilepsy.
* Severe peripheral neuropathy.
* Any other condition that, in the opinion of the investigator, would preclude safe participation in the study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Duration of stay in Phase I PACU
Timeframe: On the day of surgery
Trial details
NCT IDNCT07460310
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University