CBCT and Audiological Analysis of the TMJ-Tinnitus Relationship (NCT07460193) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
CBCT and Audiological Analysis of the TMJ-Tinnitus Relationship
Turkey (Türkiye)50 participantsStarted 2026-04-01
Plain-language summary
The aim of this study is to investigate the relationship between Temporomandibular Disorders (TMD) and subjective tinnitus at both morphological and functional levels. Current literature suggests that somatosensory inputs from the temporomandibular joint (TMJ) and masticatory muscles can modulate auditory pathways, a phenomenon known as Somatosensory Tinnitus. However, the specific role of TMJ bone morphology and critical neighboring structures, such as the Petrotympanic Fissure (PTF), in this interaction remains unclear.
In this clinical study, patients with tinnitus will undergo a comprehensive evaluation including Cone Beam Computed Tomography (CBCT) to quantitatively analyze condylar morphology and osteoarthritic changes. Additionally, audiological tests will be performed to assess the functional state of the auditory system. This multidisciplinary approach aims to clarify the biological link between TMD and tinnitus, potentially improving diagnostic protocols and highlighting the importance of TMJ stabilization in tinnitus management.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients aged 18 years and older.
* Patients presenting with otological symptoms such as tinnitus and ear pain.
* Patients diagnosed with Temporomandibular Disorders (TMD) based on clinical and radiographic examination.
* Patients who have been referred for CBCT imaging as part of their routine diagnostic process for TMD.
* Willingness to provide written informed consent to participate in the study.
Exclusion Criteria:
* Presence of objective tinnitus (e.g., vascular or muscular origin).
* History of chronic otitis media or other middle ear pathologies that could cause hearing loss or tinnitus.
* Previous history of temporomandibular joint surgery or major maxillofacial trauma.
* Presence of systemic metabolic bone diseases or inflammatory rheumatic diseases (e.g., Rheumatoid Arthritis).
* History of malignancy in the head and neck region.
* Pregnancy (due to CBCT imaging contraindication).
* Neurological or psychological disorders that would prevent cooperation during clinical and audiological examinations.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Frequency of Petrotympanic Fissure (PTF) Morphological Types
Timeframe: Baseline (at the time of the single CBCT scan during the initial clinical visit).