RecruitingPhase 1

A Study to Investigate the Pharmacokinetics of Different Formulations and Safety of AZD5004 in Healthy Participants Aged 18 to 55 Years

United States64 participantsStarted 2026-03-05

Plain-language summary

The purpose of this study is to assess the pharmacokinetics (PK), safety and tolerability of different oral formulations of AZD5004, and to evaluate the effect of food on these formulations in healthy participants.

Who can participate

Age range18 Years – 55 Years

SexALL

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Inclusion criteria

✓. of childbearing potential must not be lactating and if heterosexually active must agree to use an approved method of highly effective contraception, to avoid pregnancy.
✓. of non-childbearing potential must be confirmed at the Screening Visit.
✓. Sexually active fertile male participants with partners of childbearing potential must adhere to the contraception methods.
✓. Additional contraception must be used for the sexual partners of male study participants throughout the clinical study.

What they're measuring

Area under concentration-time curve from time 0 extrapolated to infinity (AUCinf)

Timeframe: From Day 1 to Day 22

Area under concentration-curve from time 0 to the time of last quantifiable concentration (AUClast)

Timeframe: From Day 1 to Day 22

Maximum observed concentration (Cmax)

Timeframe: From Day 1 to Day 22

Trial details

NCT IDNCT07455825

SponsorAstraZeneca

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2026-06-09

Contact for this trial

AstraZeneca Clinical Study Information Center

1-877-240-9479 information.center@astrazeneca.com

View on ClinicalTrials.gov More Healthy Participants trials