Endoscopic Sleeve Gastroplasty (ESG) Prospective Trial for Obesity (EGO-Trial)
France, Guadeloupe300 participantsStarted 2026-03
Plain-language summary
EGO-Trial is the first multicenter study in France which aims to evaluate the efficacy of Endoscopic Sleeve Gastroplasty (ESG) in patients with obesity. This project fills a critical national gap by providing real-world, multicentric data from diverse French healthcare settings, offering insight into the safety, efficacy, and variability of ESG practices across institutions
The project is expected to generate robust, multicentric clinical evidence on the safety and efficacy of ESG in patients with obesity within the French healthcare context.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients aged 18 to 75 years.
* Patients with a Body Mass Index (BMI) ≥ 30 kg/m².
* Patients who have failed non-surgical weight loss interventions (diet, exercise, pharmacological therapy).
* Patients not eligible for bariatric surgery or does not wish to undergo it.
* Patients who can undergo general anesthesia.
* Patients who are able to participate in all aspects of the study and agree to comply with all study requirements for the entire duration of the study.
* Patients who are able to fully understand the study and are willing to give their consent to participate in the study.
* Patients affiliated with the French social security system.
Exclusion Criteria:
* Patients with contraindications to endoscopic gastroplasty
* Patients with active peptic ulcer disease or significant gastroparesis
* Patients with a history of bariatric, gastric, or esophageal surgery.
* Patients who have started medication in the last 3 months that is known to cause weight gain.
* Patients with a history of uncontrolled, poorly controlled, or suspected eating disorders or psychiatric illness.
* Patients with unstable and precarious health, as determined and assessed by the investigator.
* Patients who are pregnant, breastfeeding, or of childbearing age and not using effective contraception.
* Patients who are currently excluded (as determined by a previous or ongoing study).
* Patients under judicial protection.
* Patients under guardianship, conservatorship or subject t…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Total Body Weight Loss
Timeframe: At the inclusion and 24 months after procedure