The purpose of this study is to better understand how physical characteristics, walking patterns, and a blood-based brain health marker differ between older adults with dementia and healthy older adults. Dementia is often associated with changes in physical health and movement, but these changes are not fully understood. This study asks whether people with dementia show differences in body composition, walking ability, and levels of brain-derived neurotrophic factor (BDNF), a protein involved in brain function, compared with individuals without dementia. To answer this question, participants will complete a single assessment session that includes basic physical measurements, an assessment of walking while moving at a comfortable pace, and a small blood sample collection. The information collected will be used to compare the two groups and explore possible relationships between physical function, walking patterns, and BDNF levels.
Age range
50 Years
Sex
ALL
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Gait speed during normal walking
Timeframe: At baseline (single assessment)
Stride length during normal walking
Timeframe: At baseline
Cadence during normal walking
Timeframe: At baseline (single assessment)
Cognitive function assessed by the Montreal Cognitive Assessment (MoCA)
Timeframe: At baseline (single assessment)
Cognitive function assessed by the Mini-Mental State Examination (MMSE)
Timeframe: At baseline (single assessment)