Nifedipine Extended-Release in Patients With Mild or Moderate Hypertension

Inclusion Criteria: * Men or women aged 18 years or older * Confirmed diagnosis of mild-to-moderate primary hypertension according to ESC/ESH Guidelines (12), with blood pressure readings of systolic blood pressure (SBP) \< 140 mmHg or diastolic blood pressure (DBP) \< 90 mmHg * Patient with controlled blood pressure readings during the last 4 weeks of enrollment, verified by medical records, according to ESC/ESH Guidelines (12). * Use of nifedipine as monotherapy is preferred, or in combination therapy according to clinical judgment (maintaining the combination throughout the study without changing the nifedipine dose or the doses of concomitant medications the patient is currently taking). * Voluntary participation with written informed consent. Exclusion Criteria: * Contraindication for Nifedipine use according to the established safety profile (as per the literature - Investigator's Manual): * History of documented hypertensive encephalopathy in the medical record * Evidence of secondary hypertension such as coarctation of the aorta, pheochromocytoma, hyperaldosteronism (except hypothyroidism/controlled hyperthyroidism), and obstructive sleep apnea * History of a diagnosis or condition that, in the investigator's judgment, may affect patient safety. • History of severe allergies to any medication * Subject with heart failure, New York Heart Association (NYHA) class III or IV * Severe coronary artery disease manifested by a history of myocardial infarction or unstable a…