Wound Closure Materials and Techniques in Hip and Knee Arthroplasty (NCT07439575) | Clinical Trial Compass
RecruitingNot Applicable
Wound Closure Materials and Techniques in Hip and Knee Arthroplasty
Turkey (Türkiye)90 participantsStarted 2025-11-01
Plain-language summary
This prospective randomized clinical study aims to evaluate the effects of different suture materials and wound closure techniques on wound healing, functional outcomes, and postoperative complications in patients undergoing total hip and knee arthroplasty.
A total of at least 90 adult patients undergoing primary or aseptic revision lower extremity arthroplasty will be randomized into two groups according to the wound closure material and technique used. All surgeries will be performed by the same surgical team following standardized operative protocols.
Primary outcomes include wound-related complications such as prolonged wound drainage, wound dehiscence, surgical site infection, and local inflammatory findings within 90 days postoperatively. Secondary outcomes include operative time, bleeding amount, cosmetic outcomes, and functional scores.
The results of this study are expected to help determine the most effective and safe wound closure method in lower extremity arthroplasty.
Who can participate
Age range
30 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ≥ 30 years
* Patients undergoing primary total hip arthroplasty or total knee arthroplasty
* Patients undergoing aseptic revision total hip or knee arthroplasty
* Surgery performed by the same surgical team
* Ability to provide informed consent
Exclusion Criteria:
* Age \< 30 years
* Patients receiving immunosuppressive therapy
* Patients with complicated diabetes mellitus
* Chronic venous insufficiency
* Peripheral arterial disease
* Arthroplasty performed due to malignancy
* Active or previous surgical site infection
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Since this trial is comparing different wound closure materials and techniques after hip or knee replacement, can you explain which specific methods are being tested and whether any of them differ from what you'd normally use in my surgery?
2The trial is measuring wound-related complications within 90 days after the operation — what kinds of complications are they looking at, and how would being in this study affect how closely my wound would be monitored during that recovery period?
3This study is listed as Phase NA, which typically means it's evaluating a procedure or device rather than a drug — does that change the risk profile I should be thinking about compared to my standard surgery?
4If I were enrolled, would the wound closure method used on me be chosen randomly, and would I or you know which technique was used during my recovery?
5Given that this trial is actively recruiting, would my care team be directly involved in the study, and is there a standard-of-care option outside the trial that uses a wound closure approach you'd already recommend for my specific case?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of wound-related complications within 90 days postoperatively