Evaluation of the Whitening Effect in Subjects After Professional Tooth Cleaning Procedure (NCT07438990) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Evaluation of the Whitening Effect in Subjects After Professional Tooth Cleaning Procedure
Spain50 participantsStarted 2026-03-01
Plain-language summary
The goal of this study is to learn if the toothpaste works to maintain effect of the professional tooth cleaning in adults. It will also learn about the safety of the product. The main questions it aims to answer are:
• Does the toothpaste help to maintain teeth colour after professional cleaning?
Researchers will compare whitening toothpaste to a regular toothpaste to see if it works to maintain effects of professional teeth cleaning.
Participants will:
* Use assigned toothpaste daily for 4 weeks
* Visit the clinic on the established days during 4 weeks for check ups and evaluation
Who can participate
Age range18 Years – 65 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Healthy 55 subjects
✓. Subjects of caucasian ethnicity
✓. Subjects aged between 18 and 65 years (extremes included)
✓. Subjects clinically showing stains on teeth (due to smoking, tea, coffee, wine or other food that typically stain teeth)
✓. Subjects having at least one natural teeth or central superior incisors (tooth 11 and 21) with color shade at the inclusion ≥12 and ≤30 according to R20 Bleaching shade guide
✓. Subjects registered with National Health Service (NHS)
✓. Subjects certifying the truthfulness of the personal data disclosed to the Principal Investigator or designated personnel
✓. Subjects able to understand the language used in the investigation center and the information given by the Principal Investigator or designated personnel
Exclusion criteria
✕. Subjects who do not meet the inclusion criteria.
What they're measuring
1
Change in teeth colour at by R20 Bleaching guide score at 4 weeks
Timeframe: From Baseline (after professional teeth cleaning) to end of use at 4 weeks.
✕. Subjects with all affection which could interfere with the interpretation of the results of the study
✕. Subjects planning toothcare during the study period, using dental apparatus
✕. Subjects using dental prosthesis affecting the central superior incisors, with generalized tooth recession, malocclusion or overlapping teeth in the anterior region, with presence of caries, with dental abscess or untreated gum disease, with central superior incisor (tooth 11 or 21) evaluated and filled and who performed whitening treatments less than 6 months before the study begin
✕. Subjects with any acute, chronic, or progressive disease or condition that may interfere with the study data or that the Principal Investigator considers dangerous to the subject or incompatible with the requirements of the study
✕. Subjects participating or planning to participate in other clinical trials
✕. Subjects who participated in a similar study without respecting an adequate washout period (at least one month)
✕. Subjects that have intolerances or allergies to ingredients of the study product