This is a Phase 1 study to investigate safety and pharmacokinetics of ABBV-722 and Upadacitinib following multiple oral doses in healthy adult participants.
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Maximum observed plasma concentration at steady state (Cmax,ss) of ABBV-722
Timeframe: Up to Day 6 in Period 2 and Up to Day 17 in Period 3
Time to maximum observed plasma concentration (Tmax) of ABBV-722
Timeframe: Up to Day 6 in Period 2 and Up to Day 17 in Period 3
Area under curve over the dosing interval at steady state (AUCtau,ss) of ABBV-722
Timeframe: Up to Day 6 in Period 2 and Up to Day 17 in Period 3
Observed plasma concentration at the end of the dosing interval at steady state (Ctrough,ss) of ABBV-722
Timeframe: Up to Day 6 in Period 2 and Up to Day 17 in Period 3
Maximum observed plasma concentration at steady state (Cmax,ss) of Upadacitinib
Timeframe: Up to Day 7 in Period 1 and Up to Day 17 in Period 3
Time to maximum observed plasma concentration (Tmax) of Upadacitinib
Timeframe: Up to Day 7 in Period 1 and Up to Day 17 in Period 3
Area under curve over the dosing interval at steady state (AUCtau,ss) of Upadacitinib
Timeframe: Up to Day 7 in Period 1 and Up to Day 17 in Period 3
Observed plasma concentration at the end of the dosing interval at steady state (Ctrough,ss) of Upadacitinib
Timeframe: Up to Day 7 in Period 1 and Up to Day 17 in Period 3
Number of Participants with Adverse Events (AEs)
Timeframe: Approximately up to 91 days