This is a Phase 1 study to investigate safety and pharmacokinetics of ABBV-722 and Upadacitinib following multiple oral doses in healthy adult participants.
Age range
18 Years – 65 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Maximum observed plasma concentration at steady state (Cmax,ss) of ABBV-722
Timeframe: Up to Day 6 in Period 2 and Up to Day 17 in Period 3
Time to maximum observed plasma concentration (Tmax) of ABBV-722
Timeframe: Up to Day 6 in Period 2 and Up to Day 17 in Period 3
Area under curve over the dosing interval at steady state (AUCtau,ss) of ABBV-722
Timeframe: Up to Day 6 in Period 2 and Up to Day 17 in Period 3
Observed plasma concentration at the end of the dosing interval at steady state (Ctrough,ss) of ABBV-722
Timeframe: Up to Day 6 in Period 2 and Up to Day 17 in Period 3
Maximum observed plasma concentration at steady state (Cmax,ss) of Upadacitinib
Timeframe: Up to Day 7 in Period 1 and Up to Day 17 in Period 3
Time to maximum observed plasma concentration (Tmax) of Upadacitinib
Timeframe: Up to Day 7 in Period 1 and Up to Day 17 in Period 3
Area under curve over the dosing interval at steady state (AUCtau,ss) of Upadacitinib
Timeframe: Up to Day 7 in Period 1 and Up to Day 17 in Period 3
Observed plasma concentration at the end of the dosing interval at steady state (Ctrough,ss) of Upadacitinib
Timeframe: Up to Day 7 in Period 1 and Up to Day 17 in Period 3
Number of Participants with Adverse Events (AEs)
Timeframe: Approximately up to 91 days