Effect of Bright Light Therapy on Idiopathic Scoliosis (NCT07424703) | Clinical Trial Compass
RecruitingNot Applicable
Effect of Bright Light Therapy on Idiopathic Scoliosis
China120 participantsStarted 2025-09-01
Plain-language summary
This trial aims to investigate whether morning bright light therapy can reduce the progression rate of idiopathic scoliosis in children and potentially prevent its de novo development.
Who can participate
Age range10 Years – 15 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Age between 10 and 15 years.
✓. Classified as evening chronotype based on the reduced Horne-Östberg Morningness-Eveningness Questionnaire (rMEQ), defined as a score \< 12.
✓. Has undergone radiographic evaluation (standing full-spine X-ray) for idiopathic scoliosis at the initial clinic visit.
✓. Skeletally immature (Risser sign 0-3) with a major Cobb angle \< 40 degrees at baseline.
✓. Written informed consent/assent provided by the participant and legal guardian.
✓. Willing and able to comply with the study protocol, including device use and scheduled follow-ups.
Exclusion criteria
✕. Plans to relocate outside the study area within the next 24 months.
✕. Use of medications that may interfere with circadian rhythm within the past 3 months (e.g., lithium, exogenous melatonin, melatonergic antidepressants).
✕. Trans-meridian travel across at least two time zones within the past 3 months or anticipated during the study period.
✕. Presence of any eye disease (e.g., glaucoma, retinal disease, macular degeneration) that could be exacerbated by or interfere with light therapy.
✕. Clinically diagnosed sleep disorder (e.g., narcolepsy, restless legs syndrome) or prominent medical condition known to interfere with sleep continuity and quality (e.g., moderate-to-severe eczema).
What they're measuring
1
Scoliosis Curve Angle
Timeframe: Routine follow-up visits will be scheduled 6 months apart up to 24 months
2
Angle of Trunk Rotation
Timeframe: Routine follow-up visits will be scheduled 6 months apart up to 24 months
Trial details
NCT IDNCT07424703
SponsorSecond Affiliated Hospital of Wenzhou Medical University