RecruitingNot Applicable

FACE.S-4-KIDS : A Deep Phenotyping Database of Craniofacial Anomalies During Development With 4 Pilot Projects

France3,100 participantsStarted 2025-10-16

Plain-language summary

FACE.S-4-KIDS is an ambitious database project addressing the scientific question of the variable expression of craniofacial disorders in humans, to reach a sound clinical management (diagnosis, prognosis), and the establishment of personalised treatment plans.

Who can participate

SexALL

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Inclusion criteria

✓. Patients suffering from one of the following pathologies:
✓. Patients who may or may not have benefited from genome sequencing as part of their care and who (or holders of parental authority where applicable) have consented to the conservation of the remains of their biological samples in one of these collections:
✓. Patients who have undergone craniofacial imaging (CT or MRI) as part of their care.
✓. Patients who have consulted the Genetics, Pediatrics or Maxillofacial Surgery Departments at Necker, with none of these pathologies:
✓. Patients who have benefited from genome sequencing as part of their care and who have (or holders of parental authority where applicable) consented to the conservation of the remains of their biological samples in the "Infectious Diseases" collection .
✓. Patients who have undergone craniofacial imaging (CT or MRI) as part of their treatment.

What they're measuring

Characterization of the genotypic and phenotypic components of variability in rare genetic diseases with abnormalities of craniofacial development

Timeframe: 19 years

Trial details

NCT IDNCT07422454

SponsorImagine Institute

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2031-10-31

View on ClinicalTrials.gov More Craniofacial Abnormalities trials