Tolerability and Efficacy Study of Reinnerva/Lubristil+G vs Vismed

Inclusion Criteria: * Signed informed consent * Male and female, aged 18 to 80 years * Alteration of the tear film or bilateral ocular surface discomfort resulting from one of the following conditions: Patients receiving chronic therapy with antihypertensive eye drops; Patients receiving post-ocular surgery therapy for at least 15 days * At least two of the following symptoms of dry eye: burning, stinging, dry eye sensation, foreign body sensation, photophobia * At least two of the following: Schirmer's test (8 mm lower in 5 minutes) BUT (Burning Time) less than 10 seconds Fluorescein Infection Infection (NEI) score ≥3 Exclusion Criteria: * Active keratitis caused by herpes simplex, vaccinia virus, varicella-zoster, and other viral infections of the cornea and conjunctiva * Current bacterial, fungal, and tuberculosis infections * Corneal stromal perforations and ulcers * Hypersensitivity to any of the product components * Current ocular allergy or allergic rhinitis * Participation in a clinical trial in the month prior to the start of the study * Systemic anti-acne therapy in the 6 months prior to the start of the study * Any change in systemic therapy in the month prior to the start of the study * Contact lens use in the week prior to the start of the study