Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome (NCT07421427) | Clinical Trial Compass
RecruitingNot Applicable
Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome
Egypt150 participantsStarted 2026-02-21
Plain-language summary
This study aims to evaluate the additive effect of Amantadine or Duloxetine to Pregabalin on development of post mastectomy pain syndrome
Who can participate
Age range18 Years – 65 Years
SexFEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age from 18 to 65 years.
* American society of anesthesiologists (ASA) Physical status II, III.
* Body mass index (BMI): (20-40) kg/m2.
* Type of surgery: patients undergoing modified radical mastectomy for breast cancer.
Exclusion Criteria:
* Patient refusal.
* Patients with Known sensitivity or contraindication to drug used in the study.
* History of psychological disorders and/or chronic pain and drug abuse patients.
* Previous administration of antidepressants, anticonvulsants, or opioids before surgery.
* Severe respiratory or cardiac disorders.
* Advanced liver or kidney disease.
* Previous breast surgery
What they're measuring
1
The rate of occurrence of post mastectomy pain syndrome