CompletedNot Applicable

Dental Plaque Prevention Efficacy of a Stannous Fluoride Toothpaste

United States91 participantsStarted 2024-10-16

Plain-language summary

This randomized, stratified, double-blind, two-cell parallel clinical study evaluated the dental plaque prevention efficacy of a stannous fluoride toothpaste compared to a sodium fluoride control toothpaste following a professional dental prophylaxis. Adult subjects brushed twice daily for 14 days with their assigned dentifrice. Plaque was assessed using the Lobene-Soparkar modification of the Turesky Modification of the Quigley-Hein Plaque Index at baseline, Day 1, and Day 14 following periods of oral hygiene abstention.

Who can participate

Age range18 Years – 69 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Good general health based on medical history * Minimum of 18 natural teeth with scorable surfaces * Baseline mean plaque score ≥2.0 * Willing to refrain from non-study oral hygiene products * Willing to abstain from oral hygiene prior to study visits * Able and willing to comply with study procedures Exclusion Criteria: * Known allergy to oral care products * Conditions limiting normal brushing * Significant medical conditions affecting study participation * Pregnant or nursing females * Severe periodontal disease * Recent dental prophylaxis * Recent participation in another dental study

What they're measuring

Whole-Mouth Dental Plaque Score (Turesky Modified Quigley-Hein Index)

Timeframe: Day 14 (12 hours post-brushing following 14 days of twice-daily use)

Trial details

NCT IDNCT07419737

SponsorChurch & Dwight Company, Inc.

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2024-12-04

View on ClinicalTrials.gov More Dental Plaque trials