The goal of this observational study is to understand whether vascular and structural changes in the eyes caused by diabetes can help predict which people are more likely to experience worsening diabetic retinopathy (a diabetes-related eye disease) and how these eye changes are related to cardiovascular complications. The study will include about 1,000 people with type 2 diabetes, aged 35 to 90 years, and will take place over twelve months. It may also include a retrospective component, where existing medical and imaging data collected from previous visits (within the last 1 to 5 years) will be analyzed. The main questions it aims to answer are: * Can eye vessel and tissue changes, observed through modern imaging techniques and clinical data, help better describe and predict which cases of diabetic retinopathy will become more severe? * Can these same eye changes help predict the presence and risk of cardiovascular problems-such as heart disease or stroke-in people living with type 2 diabetes?
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Change in Diabetic Retinopathy Staging
Timeframe: Baseline to 12 months
Diabetic Retinopathy (DR) Progression, measured on the OPTOS Ultra-widefield Fundus Photography (UWF-FP)
Timeframe: Baseline to 12 months
Proportion of participants with ≥15-letter loss in ETDRS Best-Corrected Visual Acuity (BCVA)
Timeframe: Baseline to 12 months
Incidence of Major Adverse Cardiovascular Events (MACE)
Timeframe: Baseline to 12 months