Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem (NCT07415733) | Clinical Trial Compass
RecruitingNot Applicable
Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem
Indonesia150 participantsStarted 2026-02-27
Plain-language summary
The primary objective of this clinical study is to evaluate the impact on gingival health when participants switch to a fluoride toothpaste without gum-health actives for 4 weeks after using a proven gum-health toothpaste for 13 weeks.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Participants need to be competent i.e., able to understand what is to take place and able to provide a free decision on agreeing to the activity/taking part in the study on this.
* Participants must be able to read and understand study instructions and any other relevant study documents.
* Have at least 20 natural teeth without subgingival calculus, including 5 assessable teeth (excluding 3rd molars) in each quadrant.
* Have a mean whole mouth BOP ≥ 10% at screening.
* Willing to follow the lifestyle and dietary restrictions as detailed in the Information Sheet for study.
Exclusion Criteria:
* Be pregnant or breastfeeding.
* Participants who participated in gum health study within 3 months prior to screening.
* Current participation in any other cosmetic studies, any dental clinical studies or clinical trials.
* Participants who have used any gum health products in the 4 weeks prior to screening.
* Obvious signs of untreated caries or significant periodontal disease, which in the opinion of the study dentist, will affect either the scientific validity of the study or if the participant to take part in the study would affect their wellbeing.
* Have more than three sites with a probing pocket depth (PPD) of ≥ 5 mm.
* Full or partial dentures wearers.
* Current orthodontic treatment.
* Smokers or those who have a recent smoking history, including e-cigarettes.
* Diabetics.
* Have had a dental prophylaxis in the month prior to enrolment or have one schedu…
What they're measuring
1
Change in gingival condition as measured by Gingival Index
Timeframe: Baseline, Week 17
2
Change in plaque level as measured by Full Mouth Plaque Score
Timeframe: Baseline, Week 17
3
Change in gingival bleeding measured by Bleeding on Probing