Study of DIOSHA S Lido Injection vs. YOUTHFILL Fine With Lidocaine in Treating Moderate to Severe⦠(NCT07412392) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Study of DIOSHA S Lido Injection vs. YOUTHFILL Fine With Lidocaine in Treating Moderate to Severe Nasolabial Folds
60 participantsStarted 2026-02-27
Plain-language summary
Study of DIOSHA S Lido Injection vs. YOUTHFILL Fine With Lidocaine in Treating Moderate to Severe Nasolabial Folds
Who can participate
Age range19 Years ā 75 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged 19 to 75 years
* Voluntarily provided written informed consent
* Moderate to severe symmetrical nasolabial folds (WSRS score 3 or 4 on both sides)
* Agree to discontinue other facial dermatologic treatments (e.g., fillers, botulinum toxin, laser) during the study
* Able to understand instructions and comply with study procedures
Exclusion Criteria:
* Active facial skin disease, infection, or untreated scars in the treatment area
* History of severe allergy or hypersensitivity to device components
* Facial aesthetic or invasive procedures in the treatment area within 6 months prior to screening
* Use of prohibited medications within required washout periods
* Participation in another interventional clinical trial within 4 weeks prior to screening or during the study
* Pregnancy, breastfeeding, or non-compliance with contraception requirements
* Any condition deemed inappropriate by the investigator
What they're measuring
1
Change from Baseline in Nasolabial Fold Severity Score at Week 24