CompletedNot Applicable

Synergistic Impact of Postural Correction Interventions and Sustained Natural Apophyseal Glides in Migraine

Pakistan44 participantsStarted 2025-01-10

Plain-language summary

This study was conducted to evaluate the synergistic impact of postural correction interventions and sustained natural apophyseal glides on severity, quality of life and disability in patients with migraine.

Who can participate

Age range

22 Years – 45 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * A diagnosis of episodic migraine made by the primary investigator according to ICHD-2. * Symptoms must include at least two of the following: Unilateral pain, Pulsating/throbbing pain, Nausea, Vomiting, Photophobia/phonophobia. * Participants should be full time employees or Desktop users. * Participants have a history of at least migraine \>4 days per month. * Participants having history of migraine lasting from 4-72 hours * Age group between 22 and 45 years. * Both gender male and female. * Participants who agree to cut-off any pharmacological treatment during study. * Participants should have an average score between 3-6 on pain intensity scale. Exclusion Criteria: * Participants having active migraine and other headache types e.g. Cluster headache. * Previous neck/head trauma from \>2 years. * Any neck/head surgery \>2 years * Spinal infections/diseases e.g. Tumor, TB spine * Any history of neurological disorders e.g. stroke, abcess, haemorrhage, haematoma * Severe Osteoporosis * Pregnancy * Upper motor neuron disease, cervical stenosis, and metabolic diseases in bone and joint. * Ongoing radiotherapy, chemotherapy, steroid therapy, or anticoagulants. * Psychiatric diseases such as phobia/obsession and depression.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Numeric Pain Rating Scale (NPRS)

Timeframe: From enrollment to the end of treatment at 4 weeks.

Migraine Specific Quality of Life Questionnaire (MSQ Version 2.1)

Timeframe: From enrollment to the end of treatment at 4 weeks.

Migraine Disability Assessment Scale (MDA)

Timeframe: From enrollment to the end of treatment at 4 weeks.

Trial details

NCT IDNCT07403175

SponsorRiphah International University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-10-31

View on ClinicalTrials.gov More Migraine trials

Who can participate

Age range

22 Years – 45 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Numeric Pain Rating Scale (NPRS)

Timeframe: From enrollment to the end of treatment at 4 weeks.

Migraine Specific Quality of Life Questionnaire (MSQ Version 2.1)

Timeframe: From enrollment to the end of treatment at 4 weeks.

Migraine Disability Assessment Scale (MDA)

Timeframe: From enrollment to the end of treatment at 4 weeks.