Using a Blood Test and Software Tool to Guide Treatment for Venous Thromboembolism

Inclusion Criteria: * Age ≥ 18 with a history of cancer-associated VTE (objectively confirmed symptomatic or incidental/unsuspected proximal lower-limb DVT, symptomatic pulmonary embolism \[PE\] or incidental PE in a segmental or more proximal pulmonary artery) and completion of between 3 and 12 months of anticoagulation with enoxaparin, dalteparin,rivaroxaban, or apixaban without current VTE-related symptoms (imaging to confirm resolution not required). Diagnosis of DVT requires evidence of one or more filling defects at compression ultrasonography, venography, CT venography, or MR venography involving at least the popliteal or more proximal veins. Diagnosis of PE requires an intraluminal filling defect in segmental or more proximal arteries. * Diagnosis of one of the following solid tumors in either advanced (i.e. unresectable) stage or receiving systemic anticancer treatment within six weeks of enrollment (maintenance therapy included): * breast cancer regardless of cytotoxic-chemotherapy status * hepatobiliary cancer regardless of cytotoxic-chemotherapy status * prostate cancer regardless of cytotoxic-chemotherapy status * non-small cell lung cancer with cytotoxic-chemotherapy received within 30 days * pancreatic cancer with cytotoxic-chemotherapy received within 30 days * bladder cancer with cytotoxic-chemotherapy received within 30 days * Signed and dated informed consent by study participant/Legally Authorized Representative (LAR). Exclusion Criteria:…