Not Yet RecruitingNot Applicable

Diagnostic Accuracy of A Diquat Quantitative Detection Kit and A Portable Mass Spectrometry System for Quantifying Diquat Concentrations in Human Blood Samples

China60 participantsStarted 2026-03-01

Plain-language summary

This is an observational, non-interventional diagnostic accuracy study designed to evaluate a diquat quantitative detection kit (ambient ionization mass spectrometry method) and a portable mass spectrometry analysis system for measuring diquat concentrations in human blood samples (whole blood/plasma), using LC-MS/MS as the clinical gold standard for comparison.

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Patients with suspected or clinically diagnosed acute diquat poisoning, providing whole blood and/or plasma samples, including qualified residual specimens retained after prior clinical testing when available.
✓. The participant or their legally authorized representative can fully understand the study purpose and procedures, voluntarily agrees to participate, and is willing and able to comply with the study requirements.
✓. Sample collection is performed according to routine clinical standards, with no apparent ethical concerns related to sample acquisition.

Exclusion criteria

✕. Abnormal sample appearance, such as visible flocculent material or other gross abnormalities.
✕. The participant is unable to provide a specimen, or the specimen does not meet testing requirements.
✕. Any participant considered inappropriate for inclusion by the investigator.

What they're measuring

Bland-Altman agreement

Timeframe: Baseline

Correlation coefficient between portable MS and LC-MS/MS

Timeframe: Baseline

Relative deviation at medical decision levels

Timeframe: Baseline

Trial details

NCT IDNCT07399574

SponsorThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-12-31

Contact for this trial

Hap Sun, MD, PhD

8613584017821 haosun_6@163.com

View on ClinicalTrials.gov More Diquat Poisoning trials

Plain-language summary

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Patients with suspected or clinically diagnosed acute diquat poisoning, providing whole blood and/or plasma samples, including qualified residual specimens retained after prior clinical testing when available.
✓. The participant or their legally authorized representative can fully understand the study purpose and procedures, voluntarily agrees to participate, and is willing and able to comply with the study requirements.
✓. Sample collection is performed according to routine clinical standards, with no apparent ethical concerns related to sample acquisition.

Exclusion criteria

✕. Abnormal sample appearance, such as visible flocculent material or other gross abnormalities.
✕. The participant is unable to provide a specimen, or the specimen does not meet testing requirements.
✕. Any participant considered inappropriate for inclusion by the investigator.