Clinical Study on TQH2722 Injection Combined With Background Therapy for Seasonal Allergic Rhinitis (NCT07398859) | Clinical Trial Compass
RecruitingPhase 2
Clinical Study on TQH2722 Injection Combined With Background Therapy for Seasonal Allergic Rhinitis
China300 participantsStarted 2026-03-19
Plain-language summary
This study is a multicenter, open-label, Phase II, single-arm clinical trial, with a planned enrollment of 200 to 300 subjects. Its primary objective is to evaluate the safety and efficacy of TQH2722 injection in the treatment of seasonal allergic rhinitis.
Who can participate
Age range18 Years – 75 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 18-75, with no gender restrictions.
* Diagnosed with seasonal allergic rhinitis.
* Positive allergen test result.
* The subjects have sufficient exposure to pollen during the pollen season.
* The subject's medical history indicates that the subject had poor control of Seasonal Allergic Rhinitis (SAR) symptoms during the previous pollen season or the subject was dissatisfied with the subjective symptom control.
* Screen for subjects who have a morning iTNSS score of ≥4 on the day of screening; at baseline visit, have a morning iTNSS score of ≥4, and have an average rTNSS score of ≥4 over the past 6 days.
* Good compliance during screening/induction period.
* Subjects with comorbid asthma should have stable medication use before the screening period and have their asthma condition assessed as stable by the investigator or specialist.
* The subjects voluntarily joined this study, signed the informed consent form, and exhibited good compliance.
* The subjects and their partners agree to take effective contraceptive measures throughout the entire study period (from the signing of the Informed Consent Form (ICF) to 3 months after the last administration of the trial drug).
Exclusion Criteria:
* Any abnormal laboratory test value during the screening period or randomization.
* Any disease that researchers consider to be unstable and may affect the patient's safety throughout the entire study period, or affect the study results or their interpretation, o…
What they're measuring
1
Number of subjects with incidence of adverse event
Timeframe: Baseline up to 4 weeks
Trial details
NCT IDNCT07398859
SponsorShanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.