The goal of this clinical trial is to develop and evaluate youth-focused intervention programs for suicide and self-harm that are tailored to the psychological, developmental, and cultural characteristics of Korean adolescents and young adults. The study examines whether two structured, mindfulness-based intervention programs-one for middle and high school students and one for young adults-reduce suicidal ideation, self-harm behaviors, depressive symptoms, and emotion-regulation difficulties. The study also aims to determine whether these clinical improvements are associated with biological changes, including alterations in resting-state functional brain activity (e.g., ALFF, ReHo, and functional connectivity) and social rhythm patterns. The main questions this study seeks to answer are: * Does the youth suicide and self-harm intervention program reduce suicidal ideation and self-injurious thoughts/behaviors? * Does the program improve mood, sleep, hopelessness, and emotion regulation? * Are improvements in clinical outcomes accompanied by changes in biological markers of suicide risk? * Researchers will compare the intervention program to usual care provided in hospitals, schools, and community mental health settings. Participants will: * Participate in the structured suicide/self-harm intervention program or receive usual care. * Complete standardized assessments of mood, sleep, emotion regulation and suicide/self-harm risk. * Undergo biological assessments, including resting-state fMRI and rhythm-related measures, at baseline and follow-up. * Be followed for up to 12 weeks.
Age range
15 Years – 30 Years
Sex
ALL
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change from Baseline in Suicidality (DSI-SS Score)
Timeframe: Baseline and Week 8, Baseline and Week 12
Change from Baseline in Functional Assessment of Self-Mutilation (FASM) Frequency Score
Timeframe: Baseline and Week 8, Baseline and Week 12
Change from Baseline in Self-Harm Screening Inventory (SHSI) Total Score
Timeframe: Baseline and Week 8, Baseline and Week 12
Change from Baseline in Circadian rhythm stability
Timeframe: Through the end of the intervention period (approximately 12 weeks)
Researcher-Defined NSSI and Suicide Attempt Frequency
Timeframe: Baseline and Week 8, Baseline and Week 12
Change from Baseline in Social Rhythm Stabilization
Timeframe: Daily throughout the intervention period (8 weeks)