Effects of Different Compression Pressure Levels on Peripheral Circulation After Surgery (NCT07394829) | Clinical Trial Compass
CompletedNot Applicable
Effects of Different Compression Pressure Levels on Peripheral Circulation After Surgery
Turkey (Türkiye)30 participantsStarted 2026-02-15
Plain-language summary
After surgery, elastic compression is commonly used on the legs to support blood circulation and reduce the risk of complications such as swelling and venous thromboembolism. In clinical practice, compression is usually applied at fixed pressure levels, although individual patients may respond differently depending on their circulation and tissue tolerance.
The purpose of this pilot study is to evaluate how different compression pressure levels affect peripheral circulation in adult patients during the early postoperative period. Participants will receive three different levels of leg compression applied sequentially under controlled conditions. Peripheral circulation will be assessed using non-invasive methods, including photoplethysmography and peripheral perfusion index measurements.
The findings of this study are expected to provide preliminary evidence on individual circulatory responses to different compression pressures and to support the development of more personalized postoperative compression strategies in future clinical practice.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged 18 to 65 years
* Undergoing elective surgery
* In the early postoperative period at the time of assessment
* Hemodynamically stable
* Intact skin on the lower extremities at the planned compression sites
* Able to understand the study procedures
* Willing and able to provide written informed consent
Exclusion Criteria:
* Peripheral arterial disease or clinically significant arterial insufficiency
* Current or previous diagnosis of deep vein thrombosis or venous thromboembolism
* Known peripheral neuropathy or sensory impairment affecting the lower extremities
* Open wounds, active infection, or dermatological conditions on the lower extremities
* Severe edema requiring therapeutic intervention beyond standard postoperative care
* Inability to tolerate compression therapy due to pain or discomfort
* Pregnancy
* Participation in another interventional clinical study during the same hospitalization period
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Peripheral Perfusion Index (PPI)
Timeframe: Baseline (T0) and during sequential compression applications (T1-T3) within the first 48 hours after surgery
2
Venous Filling Time Measured by Photoplethysmography (seconds)
Timeframe: Baseline (T0) and during sequential compression applications (T1-T3) within the first 48 hours after surgery