The goal of this study is to characterize associations between cardiorespiratory fitness, as measured by VOâ‚‚max/VOâ‚‚peak, and blood-based molecular measurements in adults. This is an observational study where research staff measures VOâ‚‚max/VOâ‚‚peak and collects fasted, resting blood samples on the same day. The main questions it aims to answer are: 1. Can a multi-analyte blood panel accurately predict directly measured VOâ‚‚max/VOâ‚‚peak? 2. How do these blood-based features vary across age, sex, and self-reported or documented physical activity profiles? 3. Are the predictor analytes able to capture changes in VOâ‚‚max/VOâ‚‚peak caused by a self-directed intervention (e.g., training for a marathon)? 4. What is the analytic reliability of the predictor biomarkers?
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A multi-analyte biomarker panel to predict maximal aerobic capacity
Timeframe: Day 1
The change in VO2max/VO2peak and a multi-analyte biomarker panel after a self-directed training program.
Timeframe: From day 1 through study completion, average of 3 months