Jafron Cytokine Adsorber During Pediatric Open-Heart Surgeries

Inclusion Criteria: * Children ≤ 10 years old at study inclusion * Children weighing at least 5 kg at study inclusion * Planned for open-heart cardiac surgery with CPB-time ≥ 120 min and aortic clamping. * Informed consent obtained from parent(s)/legal representative Exclusion Criteria: * Children having an indication to receive hemoadsorption during CPB for drugs removal or other medically justified reason * Previous enrolment into the current study * Off-pump procedure * Chronic immunosuppression (chronic corticosteroid therapy, chemotherapy, anti-leucocyte drugs, TNF blockers or else) * Known allergy to heparin or heparin induced thrombocytopenia. * Severe thrombopenia (platelets count before surgery \< 20G/L) * Parent(s)/legal representative not able to understand/read French and/or English * Participation in another conflicting research study