Human intracranial electroencephalography (EEG) can provide brain-activity correlates of memory with high spatial and temporal resolution. This project will test functional relevance of these neural signals for memory behavioral performance using novel noninvasive and invasive stimulation methods. Findings will advance understanding of brain mechanisms for memory, as is needed to accelerate progress in the treatment of memory disorders.
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Power of theta-band hippocampal iEEG activity
Timeframe: Measured during the performance of the task while research activities are completed. Measurement will take 2 to 4 hours on a single day
iEEG activity between hippocampus and the stimulated electrode
Timeframe: Measured during the performance of the task while research activities are completed. Measurement will take 2 to 4 hours on a single day
Memory task performance
Timeframe: The memory task is administered before, during and/or after stimulation from transcranial magnetic stimulation (TMS) or direct electrical stimulation (DES). The memory task will take 2 to 4 hours in a single day.