This Phase I randomized clinical trial aims to investigate the short-term effects of three commonly prescribed statins (atorvastatin, rosuvastatin, and simvastatin) at different dose levels on blood glucose homeostasis in healthy volunteers. The study will assess changes in fasting blood glucose, insulin, and C-peptide levels following two days of statin administration under controlled conditions. The research seeks to provide comparative data on the potential diabetogenic effects of these medications.
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Blood Glucose Measurements
Timeframe: before dosing and 2 days after dosing
Insulin Levels Determination
Timeframe: Before dosing and two days after dosing
C- Peptide determination
Timeframe: Before dosing and after two days of Dosing