This project measured physiological and cognitive variables to determine the effectiveness of Theacrine (TCR) as a stimulant at doses greater than those previously tested. The study will be the first TCR study to use doses relative to body weight and will investigate impacts on regular caffeine consumers. A secondary aim of the study is to determine the impact of acute TCR supplementation on salivary cortisol and sAA, two physiological measures of stress and sympathetic nervous system activation. The findings of the study will provide new insight into the effects of higher TCR dosages, contributing to the analysis of TCR as a caffeine alternative for individuals with hypertension, tachycardia, or healthy caffeine consumers wanting to avoid a stimulant with adverse or habitual effects
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change in systolic blood and diastolic blood pressure post consumption of theacrine
Timeframe: Pre-consumption, then 60, 90, 120, 150, 180 minutes post-consumption of theacrine
Change in heart rate post consumption of theacrine
Timeframe: Pre-consumption, then 60, 90, 120, 150, 180 minutes post-consumption of theacrine
Changes in executive function as a measure of cognitive performance using the Trail Making Test
Timeframe: Pre-consumption, then 60, 90, 120, 150, 180 minutes post-consumption of theacrine
Changes in attention as a measure of cognitive performance using the Flanker Inhibitory Control and Attention task
Timeframe: Pre-consumption, then 60, 90, 120, 150, 180 minutes post-consumption of theacrine
Changes in focus as a measure of cognitive performance using the Flanker Inhibitory Control and Attention task
Timeframe: Pre-consumption, then 60, 90, 120, 150, 180 minutes post-consumption of theacrine