Long-Term Clinical and Radiographic Outcomes Following Freehand and Guided Dental Implant Placeme… (NCT07373548) | Clinical Trial Compass
CompletedNot Applicable
Long-Term Clinical and Radiographic Outcomes Following Freehand and Guided Dental Implant Placement: A Randomized Controlled Trial Follow-Up
Hungary96 participantsStarted 2019-02-11
Plain-language summary
This study is a long-term clinical follow-up of a previously conducted randomized trial comparing different levels of surgical guidance in dental implant placement. The follow-up phase aims to evaluate peri-implant clinical and radiographic outcomes over an extended observation period of up to 67 months. Clinical parameters and marginal bone level changes are assessed to determine whether the accuracy benefits observed at implant placement translate into favorable long-term biological outcomes.
Who can participate
Age range18 Years – 75 Years
SexALL
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Inclusion Criteria:
* • Age between 18 and 75 years
* Partial edentulism in the maxilla or mandible involving 1-6 missing teeth, with no more than three adjacent missing teeth
* Clinical conditions suitable for implant placement as assessed by the investigator or principal investigator (adequate bone and soft tissue conditions and acceptable occlusion)
* Ability to communicate effectively with the investigators and willingness to comply with study procedures
* Provision of written informed consent
Exclusion Criteria:
* • Pregnancy or breastfeeding
* Women of childbearing potential without adequate contraception (for radiological safety reasons)
* Conditions preventing safe intraoral manipulation (e.g., limited mouth opening, pronounced gag reflex)
* Current or previous bisphosphonate therapy
* History of radiotherapy involving the maxilla or mandible
* International normalized ratio (INR) \> 2.5
* Known HIV, hepatitis B, or hepatitis C infection
* Known allergy to any component of the implant or surgical guide system
* Poor oral hygiene
* Substance abuse
* Smoking
* Untreated periodontal disease
* Any systemic disease or condition judged by the principal investigator to pose an unacceptable risk to the participant or to compromise study completion