Not Yet RecruitingNot Applicable

Telehealth-Adapted Compensatory Training and Intervention for Cognition

United States100 participantsStarted 2026-04

Plain-language summary

The goal of this clinical trial is to develop a five-week virtual cognitive training intervention for people with Mild Cognitive Impairment (MCI) based off an existing eight-week intervention. The main question it aims to answer is: • Is five weeks of training as good as eight weeks in improving cognition, quality of life, daily functioning, and mood, and in reducing caregiver burden? Researchers will compare five weeks of cognitive training to eight weeks of training to see if the shorter version is as effective as the full training. Participants will complete all activities virtually: * Complete a screening visit with a study partner (typically a family member, roommate, or close friend) to determine eligibility to participate in the study * Complete some tests of memory and thinking and some questionnaires * Attend weekly two-hour group cognitive training sessions with a trained group leader, for five or eight weeks * Redo the questionnaires and tests of memory and thinking immediately after completing the training, and three months after completing the training

Who can participate

Age range65 Years

SexALL

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Inclusion Criteria: * 65 years of age or older * Have the ability to speak and understand English * Time and willingness to commit to the completion of this study * Availability of a study partner (typically a relative, spouse, offspring, or roommate) for initial and post-intervention testing * A global Clinical Dementia Rating scale (CDR) score of 0.5 and cognitive performance of \<26 on the Montreal Cognitive Assessment (MoCA) or \<19 on the MoCA-BLIND for categorization of MCI, as determined in the screening appointment. Exclusion Criteria: * Self-reported diagnosis of dementia, stroke, traumatic brain injury, brain tumor, or a neurological disorder that affects cognition or would interfere with the ability to benefit from the study intervention (e.g., Parkinson disease, multiple sclerosis, essential tremors), or any other unstable medical condition that is predisposing to imminent cognitive or functional decline (e.g., congestive heart failure, chronic obstructive pulmonary disorder dependent on oxygen, or undergoing chemotherapy or radiation) * Major psychiatric illness (schizophrenia, intractable affective disorder, current substance dependence diagnosis or severe major depression and/or suicidality) or any history of agitation and/or delirium * Hearing or vision deficits that would interfere with standardized cognitive assessment or participation in study interventions: i.e. inability to hear through headphones (with or without hearing aids), macular degeneration or…